The municipality of Trequanda is in the province of Siena at an altitude of 453 m asl and it has a population of about 1400 inhabitants. Inside the town of Trequanda, that probably originated in the Etruscan period, the Palazzo Comunale, the church of St. Stefano and the church of SS. Pietro and Andrea that can be visited.

The village was born along a path connecting Chiusi to Siena and crossing Asciano and thanks to its position it immediately acquired a certain strategic importance.
Historical sources first mentioned Trequanda in the XII century, but more reliable information date to one century later, when the town was a property of the feudatories of the Scialenga Counts, who included Trequanda inside the borders of the territories controlled by the Ghibelline faction.
Between 1273 and 1289, Trequanda became one of the main shelters for the Siena Ghibelline exiles who were turned out by the Sienese Guelphs. This implied the aggression of the village by the Republic military forces at the end of the century. After being occupied and risking to be razed to the ground, Trequanda fell under the Sienese and it was sold to a rich merchant, Musciatto Franzesi, in 1301.
A few years later, it was recaptured by Siena and, since 1318, it became one of the centres of the Tolomei family' power, a Sienese lineage not always in line with the decisions of the Republic.
In 1553, Trequanda was one of the first villages in the Sienese country to fall in the hands of the Tuscan Grand Duchy after the descent of Charles V's Spanish imperial troops. Once it was included inside the borders of the Grand Duchy, the town experienced the Medicis' and the Lorrrains' dominations, with an interposing period of occupation by the Napoleonic army.
In 1860, it became part of the Kingdom of Italy together with the whole Tuscany.