Inside the municipality of Santa Luce the church of St. Bartolomeo, the Counts Finocchietti's palace and the Tetti family's XVII-century villa can be visited. The downtown is in the province of Pisa at 200 m asl of altitude, and it has a population of about 1500 inhabitants.

The village almost certainly has medieval origins, although in the nearby parish of St. Lucia there are the remains of a more ancient building. The same chief-town's toponym could derive either from the medieval Latin expression "Sancta Lucam" or from the parish's name itself.
The information available on this church dates to 1046, a period when it seems it was linked to the St. Angelo's parish. Only at the end of the of the XV century, it had the possibility to use its own font and break its bonds with the other parish.
Still today, Santa Luce has the appearance of a fortified village, which, at the beginning, was a property of the Counts Cadolingi from Fucecchio.
Later, in 1135, after a long diatribe among the nobles Upezzinghi, the bishop of Pisa and the Cadolingi, part of Santa Luce's territory was incorporated into the Pisan Archbishopric's properties. The town spent the following years under the influence of Pisa until the beginning of the XV century.
In 1406, Santa Luce was also part of the great number of villages and "comunitas" inside the Pisan territory that submitted to Florence, perceiving the unrelenting decadence of Pisa.
The conditions of the Florentine occupation were not any heavy, since the inhabitants of the town only had to send a huge wax-light for the St. John's festivity. Nevertheless, in 1496 Santa Luce joined Pisa in its revolt against Florence. Once they took the castle again, the Florentines decided to raze it to the ground.
In the Grand-ducal period, Santa Lucia was involved in the new administrative reorganization of 1776. In the meantime, the local economy had strengthened around agriculture and farming. With the plebiscite of 1860 it was unanimously decreed that the town had to enter the Kingdom of Italy.
In this period, also the extractive activity in the alabaster mines along the Marmolaio river developed. In 1907, the closing of some of these quarries began a long series of workers' protests that led to the growth of the local opposition movement, which fought against the Nazi-fascist occupation.