The strong>Chiesa della Madonna in Livorno was built in 1836 by the Deputazione della Patria Impresa, a citizens' association that collected public offers to thank the Virgin Mary for stopping a violent cholera epidemics. The architect Giovanni Gherardi was put in charge of the project.

The church has a Latin cross layout with one nave and two aisles and a saddleback façade realized with a local material. The watch that was previously set on the Dome's façade was put in the gable in 1882. Two XIX-century stoups stay at the entrance. The sculptures of San Michele and San Gabriele, posthmous work realized on the drawings by Giulio Guiggi and Vitaliano de Angelis, overlook them.
The high altar, financed by the town, was set here in 1854 . The left aisle is enriched with the altar of Saint John the Baptist with statues representing the saint and Mary Magdalene, two works by Paolo Emilio Demi coming from the church of the Armeni. The church has numerous chapels where works of art carried out by some of the best XIX-century sculptors are kept.
In the chapel of the Madonna della Consolazione, the wooden statues made by Guiggi and that representing Santa Lucia and Santa Gemma can be seen, while two marble statues representing the Faith and the Hope are set in the Reliquie chapel and their author is unknown. The chapel of Saint Peter the Apostle houses a XIX-century painting by Giuseppe Baldini and a "Tavola di Sant'Anna".
Then, there are the chapels of Saint Francis of Assisi with more wooden statues by Guiggi and De Angelis that represent Santa Caterina and San Domenico di Curman, but there is also the statue of San Lorenzo Martire and, lastly, the chapel without an altar dedicated to San Raffaele the Archangel.