The complex of the Medicean Villa is immediately near the Medici's ancient game reserve. The Medici were a dynasty that ruled over Florence for a long time and their name is linked to the main historical events and figures of the Florentine Renaissance.

The architect Davide Fortini was commissioned the construction of the building as settled by Cosimo I de' Medici. The villa was built on what remained of the castle of the Guidi, the feudal lords of Cerreto. The works were performed between 1564 and 1567 with the forced employment of bricklayers, stonecutters, carpenters and farmers coming from all the surroundings.
In order to raise his residence, Cosimo I did not hesitate in demolishing the village towers thus getting the material necessary for the construction.
Without any doubt, the big passion the Grand Duke has for hunting led him to build a villa in Cerreto, near his private reserve and very close to the Marshland of Fucecchio, a real paradise for water birds. The ramps that constitute its base are to be attributed to Bernardo Buontalenti's skill. They are inexplicably called "bridges" and the courtyard of the villa is called "meadow/garden". They are probably toponyms inherited from the Rocca dei Guidi.
The Villa remained a property of the Medici until the extinction of this family that almost corresponded to the arrival of the Lorraine in Tuscany. They bought it to sell it again to the Tonini family who came from Pescia and already owned a big part of the Marshland of Fucecchio, in 1781. After numerous owners followed one another, the engineer Galliano Boldrini took the Villa and donated it to the State provided that a museum was fit out inside it.
Today, the Museum of the Villa is open to the public and it houses numerous portraits of this noble family, furniture and frescoes dating to different times as well as XVIII-century tapestries. Moreover, the planning of a Hunt Historical Museum is in the pipeline. The visitors who crowd the Medicean complex can also see the room where the murder of Isabella de' Medici, the Grand Duke's daughter, was carried out by her husband Paolo Giordano Orsini. It happened for jealousy and in the course of the years it has been the subject of many novels.